CORSO DI LAUREA MAGISTRALE IN BIOINGEGNERIA

Scheda di Offerta Tesi

Titolo (provvisorio): Oxygen transport and uptake in the fibrotic liver tissue

Relatore/i: Repetto Rodolfo E-mail:
Indirizzo: Villa Cambiaso, III piano Tel.: (+39) 010 33 52471
Descrizione

Motivazione e campo di applicazione
Fibrosis is a pathological state of the liver, characterised by the formation of fibrotic regions in the liver tissue. Such fibrotic region disrupt normal blood flow and also affect oxygen transport and uptake.

Obiettivi generali e principali attività
Aim of this thesis is to build a mathematical model of blood flow and oxygen transport and consumption in the liver lobule. Both healthy and pathological conditions will be considered. The liver tissue will be modelled as a porous medium with anisotropic properties. Blood will be modelled as a Newtonian fluid. The mathematical problem will be solved making use of the finite element method using the software Comsol Multiphysics.

Obiettivi di apprendimento (strumenti tecnici e analitici, metodologie sperimentali)
The student will learn how to model flow and transport processes in porous media. The student will also improve his/her knowledge on blood flow in the microcirculation and organ perfusion.

Luogo/i in cui si svolgerà il lavoro: DICCA University of Genoa

Informazioni aggiuntive

Numero massimo di studenti: 1

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