CORSO DI LAUREA MAGISTRALE IN BIOINGEGNERIA

Scheda di Offerta Tesi

Titolo (provvisorio): Determinants of Renal Tissue Oxygenation as Measured with BOLD-MRI in Chronic Kidney Disease

Relatore/i: Fato Marco Massimo, Benedetta Toselli (DIBRIS), Beatrice Damasio (GasliniI E-mail:
Indirizzo: Viale Causa 13 - Piano -1 Tel.: (+39) 010 33 52789
Descrizione

Motivazione e campo di applicazione
Experimentally renal tissue hypoxia appears to play an important role in the pathogenesis of chronic kidney disease (CKD)

Obiettivi generali e principali attività
In this study we measured renal tissue oxygenation and its determinants in humans using blood oxygenation level-dependent magnetic resonance imaging (BOLD-MRI) under standardized hydration conditions.
Different coronal slices were selected, and a multi gradient echo sequence was used to acquire T2* weighted images.

Obiettivi di apprendimento (strumenti tecnici e analitici, metodologie sperimentali)
Obiettivi
- study different tools and methods of applying BOLD-MRI analysis on CKD
- select best tool for BOLD-MRI analysis and test feasibility on images of children and neonates

Luogo/i in cui si svolgerà il lavoro: DIBRIS - Gaslini

Informazioni aggiuntive

Numero massimo di studenti: 1

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